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Loss of CD20 and Bound CD20 Antibody from Opsonized B Cells Occurs More Rapidly Because of Trogocytosis Mediated by Fc Receptor-Expressing Effector Cells Than Direct Internalization by the B Cells

机译：由于由Fc受体表达的效应细胞介导的吞噬作用比由B细胞直接内在化引起的调理作用B细胞中CD20和结合的CD20抗体的丢失发生得更快

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Beum, Paul V.; Peek, Elizabeth M.; Lindorfer, Margaret A.; Beurskens, Frank J.; Engelberts, Patrick J.; Parren, Paul W. H. I.; van de Winkel, Jan G. J.; Taylor, Ronald P.;
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年度 2011
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1. Loss of CD20 and bound CD20 antibody from opsonized B cells occurs more rapidly because of trogocytosis mediated by Fc receptor-expressing effector cells than direct internalization by the B cells. [J] . Beum PV, Peek EM, Lindorfer MA, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2011,第6期

机译：由于表达Fc受体的效应细胞介导的吞噬作用，与调理B细胞的CD20和结合的CD20抗体相比，B细胞直接内在化的速度更快。
2. Human neutrophils mediate trogocytosis rather than phagocytosis of CLL B cells opsonized with anti-CD20 antibodies [J] . Valgardsdottir Rut, Cattaneo Irene, Klein Christian, Blood: The Journal of the American Society of Hematology . 2017,第19期

机译：人中性粒细胞介导针刺症，而不是用抗CD20抗体透露CLL B细胞的吞噬作用
3. Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell-mediated B-cell cytotoxicity. [J] . Mossner E, Brunker P, Moser S, Blood: The Journal of the American Society of Hematology . 2010,第22期

机译：通过改造具有增强的直接和免疫效应细胞介导的B细胞细胞毒性的新型II型抗CD20抗体，提高CD20抗体疗法的功效。
4. Advantage of Alagln as an Additive to Cell Culture Medium: Application to Anti-CD20 Chimeric Antibody-Producing POTELLIGENT~(TM) CHO Cell Lines [C] . Yasufumi Imamoto, Hisaya Tanaka, Ken Takahashi, Annual and International Meeting of the Japanese Association for Animal Cell Technology . 2010

机译：Alagln作为细胞培养基添加剂的优势：在抗CD20嵌合抗体产生滴度〜（TM）CHO细胞系
5. Regulation of CD20 in rituximab-resistant cell lines (RRCL) and B-cell non-Hodgkin's lymphoma (B-NHL) [D] . Tsai, Ping-Chiao 2012

机译：CD20在利妥昔单抗耐药细胞系（RRCL）和B细胞非霍奇金淋巴瘤（B-NHL）中的调节
6. Immunobiology: Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity [O] . Ekkehard Mössner, Peter Brünker, Samuel Moser, -1

机译：免疫生物学：通过设计具有增强的直接和免疫效应细胞介导的B细胞细胞毒性的新型II型抗CD20抗体提高CD20抗体疗法的功效
7. Loss of CD20 and Bound CD20 Antibody from Opsonized B Cells Occurs More Rapidly Because of Trogocytosis Mediated by Fc Receptor-Expressing Effector Cells Than Direct Internalization by the B Cells [O] . Beum, Paul V., Peek, Elizabeth M., Lindorfer, Margaret A., 2011

机译：由于由Fc受体表达的效应细胞介导的吞噬作用比由B细胞直接内在化引起的调理作用B细胞中CD20和结合的CD20抗体的丢失发生得更快

Loss of CD20 and Bound CD20 Antibody from Opsonized B Cells Occurs More Rapidly Because of Trogocytosis Mediated by Fc Receptor-Expressing Effector Cells Than Direct Internalization by the B Cells

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